The Associated Press: Skin Cancer Drug Said to Show Promise

"A very early test of an experimental drug seemed to slow the spread of advanced deadly skin cancer in a small study, the drug's U.S. developer reported in preliminary findings Wednesday. Synta Pharmaceuticals Corp. of Lexington, Mass., reported that patients with advanced melanoma who got the drug survived an average of 3.7 months without new cancer lesions, compared to 1.8 months for those who got the standard treatment. The treatment, given as a pill, is so early in development it doesn't have a name. It must pass muster in much more rigorous testing before the company seeks U.S. approval. Synta's drug is one of several in development by other companies trying a new strategy against cancer — killing tumor cells by overloading them with oxygen. 'We are taking advantage of the Achilles heel of cancer cells,' said Dr. Anthony Williams, vice president of clinical research at Synta Pharmaceuticals. The drug has no effect on normal cells, which can adjust to higher levels of oxygen that cause cancer cells to self-destruct."